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10 Best Supplements for Men Over 40

By PureHealth Research Apr 11, 2023

Medically reviewed by Medically reviewed by Our Experts

Medically reviewed by Medically reviewed by Our Experts

Medically reviewed by 11 min read

Medically reviewed by 7 citations

A Senior in a Colorful Outfit Holding Weights After Learning About 10 Best Supplements for Men Over 40

As you’ve grown older, have you considered incorporating the best supplements for men over 40 into your regimen, especially when you’ve learned about certain foods that kill testosterone? If so, you’re heading in the right direction to ensure lasting health and vitality.

In our younger years, many of us are engrossed in careers, family commitments, and vibrant social lives, often sidelining our health in the process. It’s easy to take one’s health for granted during these bustling times. The rapid-paced years filled with stress, late-night outings, smoking, poor dietary choices, consumption of foods that decrease testosterone, and excessive alcohol eventually weigh on our well-being. As the 40s roll in, the repercussions of past lifestyle choices become evident through emerging health concerns.

Key Article Findings

  • Prioritize Health: As you age, prioritize balanced nutrition, exercise, sleep, stress management, and regular health check-ups.
  • Essential Supplements: Consider supplements like creatine for muscle energy, leucine for muscle maintenance, and B-complex vitamins for overall health.
  • Product Highlight – Exuberant: A supplement containing nutrients like L-arginine and epimedium aimed at boosting stamina and vitality in men over 40.

You’re Never Too Old to Improve Your Health 

Make these critical changes in your lifestyle to have a healthy future:  

  • Eat a balanced diet with adequate proteins and fiber. 
  • Exercise daily and keep yourself hydrated. 
  • Get eight hours of sleep. 
  • Reduce alcohol intake and smoking.  
  • Try to manage stress. 
  • Go for regular health checkups. 
  • Take male energy supplements as advised by your physician. You can make the top men’s supplements over 40 your go-to solution for energy and vitality.   

Why Should You Consider Supplements as a Man Over 40?  

Mature Male Is Having Intense Workout in the Gym

As a man over 40, you should never be worried about the lack of vigor and stamina you once had in your 20s. Consider your nutritional requirements and check your diet carefully. Find out what is lacking in your meals.

For instance, your protein intake might not be enough, or your diet may not include enough selenium or leucine. Maintaining a balance between macronutrients and micronutrients can often be hard to achieve. So, what can you do? The best way to fill the nutritional gap and stay healthy is with the help of the best supplements for men over 40.  

Best Supplements for Men Over 40  

Are you full of self-disgust because you do not feel healthy from the inside anymore? The lack of energy and tremendous lethargy could be due to the inadequate intake of vital nutrients. Your body needs nourishment to vivify itself.

There are so many supplements for men over 40 available on the market, so how do you know which to buy? Here is our list of the best men’s supplements for those over 40 that you need to maintain a healthy and fulfilling life. 

1. Creatine 

Creatine Powder Next to Pills and Granola Bar

Creatine is an amino acid responsible for building adenosine triphosphate (ATP). It provides energy to muscles during contraction. You can consume red meat, seafood, and more for sufficient daily creatine requirement. Also, it would be best if you took a trusted men’s supplement over 40. Ensure it contains the goodness of creatine. 

Creatine will help you work out for long hours because it boosts your performance. It also shields your muscles from fatigue. With the decrease in testosterone levels, muscle mass reduces. Creatine supports the development of lean muscles and improves your athletic performance. However, make it a point to take plenty of water to keep dehydration at bay.  

2. Leucine 

Leucine Powder and Pills

Losing muscle mass fast is one of the woes of entering the 40s club. Make leucine a part of your diet to maintain your muscle mass. Leucine triggers muscle protein synthesis and helps muscles grow and repair after an intense workout. It plays a critical role in balancing your blood sugar levels as well.  

Leucine nourishes your tissue, bones, and organs, so it is one of the vital supplements men over 40 need to gain muscle strength. Include salmon, chickpeas, brown rice, eggs, soybeans, nuts, and beef in your diet to increase leucine intake and adequately nourish the body. To overcome any deficit, consume leucine with your protein shake for the best results.  

3. B-Complex Vitamins 

Various B-Complex Vitamins

One of the best supplements for men over 40 are the vitamins belonging to the B-complex group. Sometimes, despite taking a healthy diet, you might not receive adequate nutrition. The reasons could be your busy schedule, hectic lifestyle, etc. If you do not get proper sustenance from your diet, you may fall prey to different diseases due to the deficiencies of specific vitamins and minerals. 

As you get older, your body’s ability to absorb these vitamins from your food reduces. Hence, using these multivitamins as supplements will ensure you get the required micronutrient dosage to prevent diseases like anemia, eye problems, cardiovascular diseases, gastric disturbances, cancer, cognitive defects, diabetes, and more.

Remember that your intake must not surpass the recommended daily allowance of these vitamins. It is best to take vitamin B complex along with food for better absorption. 

4. Selenium 

Selection of Foods That Are High in Selenium

To get this trace element naturally from your diet, eat Brazil nuts, fish, and organ meat like liver and kidney. Selenium prevents oxidative damage of cells due to free radicals. Some free radicals are inevitable because they are the by-product of metabolism.

Exposure to environmental toxins leads to the formation of these free radicals within our bodies. Antioxidants like selenium donate electrons to the unbound electrons within these free radicals to neutralize them.

Oxidative stress causes varied diseases like arthritis, cancer, premature aging, and age-related disorders of the heart. Take multivitamins and a selenium-fortified supplement for men over 40 from reputed brands for impressive results.  

5. Saw Palmetto 

Saw Palmetto on a Wooden Spatula

Reproductive problems can hinder the self-esteem of a man. There is a possible solution to this issue, thanks to saw palmetto! It comes from palm trees and is often available to men in over-40 supplements.

Saw palmetto’s effectiveness gradually helped it make its way into the ayurvedic realm to treat diseases of the prostate and urinary system. The supplement maintains prostatic health and prevents benign enlargement of the prostate gland and other urinary dysfunctions that are commonplace age-related issues. 

The body absorbs this fat-soluble supplement quickly, and the best part is you need not worry about any significant side effects when you take the supplement with food. This highly effective active compound will help you feel alive again!  

6. Tribulus Terrestris 

Stone Mortar With Tribulus Terrestris 

As men age and pass 40, their testosterone levels may start to decline, which can lead to a lower sex drive, weaker bones, fatigue, weight gain, hair thinning, and more. Some studies have suggested that Tribulus terrestris might help in boosting testosterone levels, although further research is needed to confirm these findings, as the evidence surrounding its effectiveness, are mixed and inconclusive.

Apart from its potential impact on testosterone, Tribulus terrestris has been used in traditional Ayurvedic medicine for various health issues. It may provide benefits for men over 40, such as supporting kidney function, promoting healthy blood pressure, alleviating urinary tract infections (UTIs), and reducing chronic pain. 

7. Fenugreek 

A Bowl of Fenugreek Next to a Glass of Liquid

Not many people know this, but fenugreek has brilliant effects on men’s health, especially for those above 40. Fenugreek lowers the harmful cholesterol levels in the bloodstream and boosts stamina in men with low metabolism rates.

When the cholesterol levels are lower, even sexual organs work better because blood circulation through the arteries and blood vessels happens uninterrupted. Healthy blood flow through the arteries reduces the chance of erectile dysfunction.  

Fenugreek has an excellent store of antioxidants. The flavonoid called naringenin within fenugreek improves cardiovascular health, thereby increasing vigor and stamina in men, allowing them to age like fine wine. So, if you are looking for an effective supplement for men over 40, fenugreek should be your one-stop solution.  

8. Epimedium 

A Pile of Epimedium

Epimedium is the active component within horny goat weed that can amp up the overall masculine health of a man. Scientific research shows that epimedium is an outstanding element that boosts libido by increasing blood circulation through the penile arteries.

The bioactive compound called diindolylmethane present within horny goat weed effectively controls abnormal growth of cells in the prostate and promotes healthy hormone balance. It is one of the vital supplements for men over 40 to consider.  

9. L-Arginine 

L-Arginine Powder

Want to boost the formation of muscle cells? L-arginine is the amino acid you can trust. Some studies show that L-arginine benefits men who want to exercise for longer durations. It supports the internal systems to build protein, facilitating muscle mass growth. It is also believed that L-arginine helps in improving immunity and aids in better circulation.  

Naturally, you can find L-arginine in fish, nuts, whole grains, soy, and dairy products. Most advanced supplements for men over 40 include this significant element which helps maintain a wholesome lifestyle.  

10. D-Aspartic Acid 

A Molecular Concept of D-Aspartic Acid

This endogenous amino acid helps to release testosterone in men. D-aspartic acid boosts the motility of spermatozoa. When you include this amino acid supplement in your diet, your male vitality and vivacity increase tenfold. 

D-aspartic acid helps you defy age-related fertility issues. The best products for men over 40 are supplements with this highly effective component. Do not let low sperm motility and lack of energy affect your sexual confidence.  

Unlock Your Potential 

Man Over 40 Lifting a Dumbbell

Now that you are in your 40s, do you wake up feeling tired? Is sleep inadequate to replenish your energy? Are you unsure of how your physical health and stamina will affect the quality of your life? Well, you need not worry anymore. Dr. Holly Lucille’s recommended Exuberant could keep your youthful charm intact and make you forget your age. 

PureHealth Research’s supplement is the perfect blend of nutrients good and gold for health, such as:   

  • L-arginine 
  • Tongkat Ali 
  • Ashwagandha 
  • D-aspartic acid 
  • Leucine 
  • Epimedium 
  • Saw palmetto 
  • Tribulus terrestris 
  • Vitamin D4 
  • Fenugreek 
  • Zinc  
Product Image


Product Image


Boost your confidence and overall quality of life to prevent mid-life blues from ruining your personal life and happiness. Give yourself the boon of the new life you have always dreamed of! This is the holy grail to re-energize and revitalize your mind, body, and soul.

Shop Now


Boost your confidence and overall quality of life to prevent mid-life blues from ruining your personal life and happiness. Give yourself the boon of the new life you have always dreamed of! This is the holy grail to re-energize and revitalize your mind, body, and soul.



Shop Now




Boost your confidence and overall quality of life to prevent mid-life blues from ruining your personal life and happiness. Give yourself the boon of the new life you have always dreamed of! This is the holy grail to re-energize and revitalize your mind, body, and soul.

Shop Now

This scientifically proven formula will enhance your stamina and performance, making you look and feel younger. The cherry on the cake is Exuberant has no known adverse side effects, and you can take it over long periods. 

Still unsure about this product? Visit the PureHealth Research website and read hundreds of reviews from satisfied customers who trust the goodness of Exuberant. Hurry, get your bottle right now before the stock clears. Cheers to the beginning of a younger life. Be a brawny young brute, even in your 40s! 

Final Thoughts 

By now, you know the importance of supplements and how they function to protect you from major diseases and work to improve the overall quality of your life. The fact that you have started thinking about the best supplements for men over 40 is good news! However, remember that supplements are not meant to replace the main meal.  

Combining supplements with healthy lifestyle choices, such as taking necessary steps for effective weight loss, will ensure you always have a good life. So, choose wisely and live happily! The revolutionary product by PureHealth Research, Exuberant, can offer you the natural energy lacking in your life. So why wait?

Why should men over 40 consider taking supplements?

As men age, their nutritional needs change, and it becomes harder to obtain all essential nutrients from diet alone. Supplements can help fill nutritional gaps, support muscle maintenance, boost energy levels, and improve overall health, especially in combating age-related health issues.

What are the benefits of taking creatine for men over 40?

Creatine supports muscle energy production, enhances workout performance, and helps maintain lean muscle mass, which tends to decline with age. It also helps prevent muscle fatigue, allowing for longer and more effective exercise sessions.

How does leucine benefit men over 40?

Leucine is crucial for muscle protein synthesis, which helps in muscle growth and repair. It also aids in balancing blood sugar levels and supports overall tissue, bone, and organ health.

What role do B-complex vitamins play in men’s health over 40?

B-complex vitamins support overall health by enhancing energy levels, improving cognitive function, and preventing deficiencies that can lead to conditions like anemia, cardiovascular diseases, and cognitive decline. They are essential for maintaining healthy metabolism and reducing fatigue.


WebMD. (n.d.). (2024). Selenium: Uses, Side Effects, Interactions, Dosage, and Warning. WebMD.


WebMD Editorial Contributors. (2023). Top foods high in leucine. WebMD.


Encyclopaedia Britannica. (n.d.). (2024). Adenosine triphosphate. In Encyclopaedia Britannica.


Mouser, J. G., Loprinzi, P. D., & Loenneke, J. P. (2016). The association between physiologic testosterone levels, lean mass, and fat mass in a nationally representative sample of men in the United States. Steroids, 115, 62-66.


Atherton, P. J., & Smith, K. (2012). Muscle protein synthesis in response to nutrition and exercise. Journal of Physiology, 590(Pt 5), 1049-1057.


Pizzino, G., et al. (2017). Oxidative stress: Harms and benefits for human health. Oxidative Medicine and Cellular Longevity, 2017, 8416763.


Mayo Clinic Staff. (n.d.). (2022). Urinary tract infection. Mayo Clinic.

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