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How to Normalize an Overactive Immune System

By PureHealth Research Sep 23, 2024

Medically reviewed by Medically reviewed by our experts

Medically reviewed by 10 min read

Medically reviewed by 7 citations

A woman in a meditative pose, sitting cross-legged with hands in a prayer position, surrounded by a visual representation of viruses being blocked by an invisible shield, symbolizing immune protection.

An overactive immune system can significantly impact your health, causing a range of symptoms from unexplained fatigue to persistent allergies. If you’re wondering how to normalize an overactive immune system, you’re not alone. Many people struggle with this condition, which occurs when the body’s defense mechanisms work too hard, even without real threats.

The good news is that understanding how to normalize an overactive immune system naturally is possible, often through lifestyle changes. This guide will explore the causes, symptoms, and practical approaches to help you regain control over your health.

Key Insights

  • Genetic predisposition, lifestyle choices, and the environment are all thought to play a role in the development of this condition. The exact causes, however, are not entirely known yet.
  • Individuals wondering how to normalize an overactive immune system can try several lifestyle changes to improve their condition. Some of these include switching to an anti-inflammatory diet, doing regular exercise, managing stress, consuming supplements, and trying out therapies.

What Is an Overactive Immune System?

Your immune system is your body’s defense mechanism against harmful invaders like viruses and bacteria. However, sometimes this system can become overactive, leading to a range of health problems.

An overactive immune system occurs when your body’s defense mechanisms work too hard, even when there’s no real threat present. This can result in your immune system mistakenly attacking your own healthy cells and tissues.

One of the most common indicators of an overactive immune system is being allergic to harmless things. Some of the most prevalent allergies is to peanuts, and peanut butter can also trigger allergic reactions in sensitive individuals. These reactions can range from mild skin irritations to severe anaphylaxis, depending on the person, that’s why some people can think that peanut butter can cause acne. Additionally, skin allergies such as eczema and respiratory issues like asthma can also be linked to an overactive immune response.

Want to learn more about the immune system? Read our article that covers seven facts about the immune system!

Symptoms of an Overactive Immune System

Common signs that you may have an overactive immune system include:

  • Frequent allergies
  • Autoimmune disorders
  • Chronic fatigue
  • Unexplained weight changes
  • Hair loss
  • Dry skin
  • Joint pain
  • Difficulty recovering from infections

Causes of an Overactive Immune System

The exact cause of an overactive immune system isn’t always clear. However, several factors may contribute:

  • Genetic predisposition
  • Environmental triggers
  • Lifestyle factors
  • Chronic stress

How to Normalize an Overactive Immune System

While you can’t always prevent an overactive immune system, there are several ways to manage and normalize it:

1. Follow an Anti-inflammatory Diet

What you eat can significantly impact your immune function. To help normalize an overactive immune system naturally, consider:

  • Increasing your intake of fruits and vegetables
  • Consuming more whole grains and lean proteins
  • Including healthy fats in your diet
  • Limiting processed foods, sugar, and saturated fats
A colorful display of healthy, anti-inflammatory foods including salmon, blueberries, spinach, strawberries, pumpkin seeds, almonds, broccoli, walnuts, oats, and olive oil, arranged in small dishes and plates on a white surface.

This dietary approach not only helps in managing inflammation but also supports overall immune function and reduces the risk of chronic diseases. The evidence suggests that making these dietary changes can lead to significant health benefits and improved quality of life

2. Exercise Regularly

Regular exercise is a cornerstone of a healthy lifestyle and plays a crucial role in reducing inflammation and enhancing immune function. Below are recommended exercise durations and types.

  • 150 minutes of moderate-intensity exercise per week, or
  • 75 minutes of vigorous-intensity exercise per week
A woman with a ponytail wearing a white tank top, using suspension straps during a workout at the gym. She is focused on her strength training routine.

Options include yoga, cycling, swimming, or resistance training.

3. Manage Stress

Chronic stress can negatively impact your immune system. Try these stress-management techniques to help normalize an overactive immune system:

  • Meditation
  • Journaling
  • Yoga
  • Ensuring adequate sleep (aim for 7-9 hours per night)
A serene woman sitting cross-legged in a peaceful living room, practicing meditation. She is in a relaxed state with her eyes closed, wearing a green tank top and black leggings, surrounded by calming plants and soft, natural light filtering through the window.

By incorporating these stress-management techniques into your routine, you can help mitigate the negative effects of chronic stress on your immune system and overall health.

4. Consider Supplements

Certain supplements may help support immune function and potentially assist in normalizing an overactive immune system. Always consult with a healthcare provider before starting any new supplement regimen. Our top picks are:

  • Omega-3 fatty acids
  • Vitamin D
  • Zinc

Omega-3s have anti-inflammatory properties that may help modulate immune function. While you can get omega-3s from foods like fatty fish, some people turn to supplements for a more concentrated dose.

Often called the “sunshine vitamin,” Vitamin D plays a crucial role in immune function. Some studies suggest that Vitamin D deficiency may be linked to autoimmune disorders.

Zinc is essential for the development and function of immune cells. It may help regulate the immune response and reduce inflammation.

One innovative option in this category is Nano Powered Omega 3. This supplement uses nanotechnology to break down larger omega-3 molecules into smaller particles, potentially increasing absorption by the body. It contains:

  • Omega-3 DHA
  • Omega-3 EPA
  • Astaxanthin, a potent antioxidant

The combination of these ingredients may help support overall health and potentially assist in calming an overactive immune response.

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Remember, while supplements can be helpful, they’re not a substitute for a balanced diet and healthy lifestyle. It’s also important to note that the effectiveness of supplements can vary from person to person. What works well for one individual may not have the same effect on another.

5. Explore Therapies

Another good way to normalize an out-of-control immune system is by trying out therapies:

  • Intravenous immunoglobulin (IVIG) therapy
  • Dry skin brushing
  • Therapeutic massage
A person receiving a relaxing back massage from a therapist. The therapist's hands are gently working on the muscles of the client's upper back in a peaceful setting.

Bonus Tips: Taking antibiotics can also represent a struggle. Wondering how to rebuild your immune system after antibiotics? If so, below are a series of lifestyle-related steps you can follow in our linked article.

Two Tasty Autoimmune Diet Recipes

A proper diet is an essential strategy for managing an overactive immune system. Here are a few easy dishes that may be helpful.

Recipe 1: Crispy Salmon Kale Salad With Tahini Dressing

This nutrient-packed salad combines crispy salmon, hearty kale, and a tangy tahini dressing for a delicious and healthy meal. Rich in omega-3 fatty acids, fiber, and vitamins, this recipe is perfect for supporting overall health, including immune function.

A bowl of fresh salmon salad featuring a sesame-crusted salmon fillet, arugula, lemon wedge, tofu cubes, and sliced vegetables such as carrots, offering a healthy and balanced meal.

Ingredients 

For the dressing:
  • 3-4 small limes, juiced
  • 1/2 teaspoon chili pepper flakes
  • 1/2 cup tahini
  • 1 tablespoon maple syrup
  • Water (as needed for consistency)
For the salmon:
  • 5 lbs. skinned salmon
  • 1 tablespoon olive oil
  • Spices to taste:
    • Chipotle powder
    • Onion powder
    • Dried oregano
    • Garlic powder
    • Salt
For the salad:
  • 10 oz. chopped kale
  • 1 pomegranate, seeds removed
  • 2 avocados, sliced
  • 1/2 cup chopped pistachios
  • 1 pint cherry tomatoes, sliced
  • 1 cup shaved fontina cheese (optional)

Instructions

Step 1: Prepare the dressing
  1. In a sealable container, whisk together lime juice, chili pepper flakes, and tahini until smooth.
  2. Add small amounts of water until you reach your desired consistency.
  3. Stir in maple syrup, adjusting to taste.
  4. Set aside.
Step 2: Cook the salmon
  1. Pat the salmon dry with paper towels.
  2. Cut the salmon into 1.5-inch cubes.
  3. In a bowl, mix the spices (chipotle powder, onion powder, dried oregano, garlic powder, and salt).
  4. Toss the salmon cubes in the spice mixture until evenly coated.
  5. Heat olive oil in a large skillet over medium-high heat.
  6. Cook the salmon in batches, about 4 minutes per side, turning gently. Set aside.
Step 3: Prepare the salad
  1. In a large bowl, massage the chopped kale with your hands for a few minutes until it softens.
  2. Add pomegranate seeds, sliced avocados, chopped pistachios, and sliced cherry tomatoes to the kale.
  3. If using, add the shaved fontina cheese.
Step 4: Assemble and serve
  1. Gently toss the salad ingredients together.
  2. Add the crispy salmon cubes to the salad.
  3. Drizzle with the tahini dressing just before serving.

Nutrition Tip

This salad is rich in omega-3 fatty acids from the salmon, which may help support heart and brain health. The kale provides fiber and vitamins, while the nuts and avocado offer healthy fats. Remember to control portion sizes, especially with the dressing, to maintain a balanced meal.

Recipe 2: Quinoa and Black Bean Bowl With Sweet Potato and Cilantro-Lime Dressing

This vibrant and nutritious bowl combines protein-rich quinoa and black beans with colorful vegetables and a zesty cilantro-lime dressing. Packed with fiber, vitamins, and minerals, this meal is perfect for supporting overall health and maintaining a balanced diet.

A vibrant bowl filled with nutritious ingredients including quinoa, roasted brussels sprouts, avocado slices, sweet potatoes, tofu, and leafy greens, drizzled with a creamy dressing.

Ingredients

For the bowl:
  • 1 cup quinoa, rinsed
  • 2 cups water or vegetable broth
  • 1 can (15 oz) black beans, rinsed and drained
  • 1 cup corn kernels
  • 1 red bell pepper, diced
  • 1 avocado, diced
  • 1 small red onion, finely chopped
  • 1 cup cherry tomatoes, halved
  • 1/4 cup fresh cilantro, chopped
For the dressing:
  • 1 lime, juiced
  • 2 tablespoons olive oil
  • 1 teaspoon ground cumin
  • 1/2 teaspoon chili powder
  • Salt and pepper to taste
Optional toppings:
  • Crumbled feta cheese
  • Sliced jalapeños
  • Hot sauce

Instructions

Step 1: Cook the quinoa
  1. In a medium saucepan, combine quinoa and water (or vegetable broth).
  2. Bring to a boil, then reduce heat to low and simmer for 15 minutes.
  3. Remove from heat, fluff with a fork, and set aside to cool slightly.
Step 2: Prepare the vegetables
  1. While the quinoa is cooking, dice the red bell pepper and avocado.
  2. Finely chop the red onion.
  3. Halve the cherry tomatoes.
  4. Chop the fresh cilantro.
Step 3: Make the dressing
  1. In a small bowl, whisk together lime juice, olive oil, ground cumin, and chili powder.
  2. Season with salt and pepper to taste.
Step 4: Assemble the bowl
  1. In a large bowl, combine the cooked quinoa, black beans, corn, red bell pepper, red onion, and cherry tomatoes.
  2. Pour the dressing over the quinoa mixture and toss gently to combine.
  3. Carefully fold in the diced avocado.
Step 5: Serve
  1. Divide the mixture into serving bowls.
  2. Sprinkle with chopped cilantro.
  3. Add optional toppings like crumbled feta cheese, sliced jalapeños, or hot sauce if desired.

Nutrition Tip

This bowl is a nutritional powerhouse. Quinoa provides complete protein and essential amino acids, while black beans offer fiber and additional protein. The variety of vegetables contributes vitamins, minerals, and antioxidants. The olive oil in the dressing provides heart-healthy fats. For a lower-sodium option, use low-sodium or no-salt-added black beans and adjust seasoning to taste.

Enjoy your colorful and nutritious Quinoa and Black Bean Bowl!

Conclusion

Understanding and managing an overactive immune system is crucial for overall wellness. When your body’s defense mechanism goes into overdrive, it can lead to a range of health issues, from allergies to joint pain and unexplained weight changes. While the exact causes aren’t fully understood, factors like genetics, lifestyle, and environment likely play a role.

Throughout this article, we’ve provided two easy-to-follow recipes featuring anti-inflammatory ingredients and gut-friendly foods. These dishes not only taste great but also support your immune health. By incorporating these meals into your diet and following the lifestyle tips we’ve discussed, you can take proactive steps towards balancing your immune system and improving your overall health.

Remember, managing an overactive immune system is a journey. Be patient with yourself and consistent in your efforts. With time and the right approach, you can work towards a more balanced immune response and better overall well-being.

How to Normalize an Overactive Immune System Naturally?

You can naturally normalize it by following some simple approaches. Some of them are observing a healthy diet, exercising, and managing stress.

How to Reset the Immune System?

The best way to do so is by adjusting your current lifestyle. Increasing physical activity, limiting the consumption of processed foods, and getting sufficient sleep are all steps that can help.

Can You Slow Down an Overactive Immune System?

Yes, you can. Use supplements and make healthy lifestyle changes. Corticosteroids work as well. However, they present severe side effects and should only be taken under professional supervision.

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Clinic, C. (2024). Is your immune system working overtime? Cleveland Clinic.

https://health.clevelandclinic.org/overactive-immune-system
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https://nutritionsource.hsph.harvard.edu/healthy-weight/diet-reviews/anti-inflammatory-diet/
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Nieman, D. C., & Wentz, L. M. (2019). The compelling link between physical activity and the body’s defense system. Journal of Sport and Health Science/Journal of Sport and Health Science, 8(3), 201–217.

https://www.sciencedirect.com/science/article/pii/S2095254618301005?via%3Dihub
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Solan, M. (2023). How much sleep do you actually need? Harvard Health.

https://www.health.harvard.edu/blog/how-much-sleep-do-you-actually-need-202310302986
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Yang, C., Leung, P. S. C., Adamopoulos, I. E., & Gershwin, M. E. (2013). The Implication of Vitamin D and Autoimmunity: a Comprehensive Review. Clinical Reviews in Allergy & Immunology, 45(2), 217–226.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047889/#:~:text=increasing%20evidence%20demonstrates%20a%20strong%20association%20between%20vitamin%20D%20signaling%20and%20many%20biological%20processes%20that%20regulate%20immune%20responses.
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